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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Kidney Int. 2020 Nov 1;99(3):620–631. doi: 10.1016/j.kint.2020.09.031

Figure 7. DMOG reduced tubulointerstitial injury but did not directly affect glomerular cells.

Figure 7.

Renal function, assessed by BUN and Scr, was worsened in folic acid versus vehicle mice, and improved only numerically after DMOG intervention (A). Ex vivo bioluminescence images. Quantitation of collagen I signal in folic acid+DMOG versus folic acid mice (B). In response to DMOG after folic acid injury, collagen I immunostaining in whole kidney cortex was decreased (C), the proportion of atubular glomeruli was reduced (D), and glomerular WT-1 density was not changed (E).