Figure 9. Tubulointerstitial injury improvement resulted in less severe subsequent glomerular Injury.
Ten days after podocyte injury by LMB2 injection, glomerulosclerosis was decreased in the non-fibrotic areas in when DMOG was added to mice with folic acid +podocyte injury (A). Glomerular collagen IV staining was also decreased in glomeruli in non-fibrotic areas by added DMOG (B), the glomerular density of WT-1 positive cells was higher (C) and glomerular nephrin expression was increased (D).