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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Psychopharmacology (Berl). 2020 Nov 23;238(3):699–710. doi: 10.1007/s00213-020-05722-6

Figure 1: Fentanyl self-administration in a home-cage drinking in the dark task.

Figure 1:

(A) Mice were given two bottles of fentanyl (10 μg/mL) for 2 h/day. After 11 sessions of drinking, quinine was added to the bottles. (B) Total fentanyl consumption in female (=green) and male (=white) mice over the first 11 sessions. *p < 0.05 vs. females on that session (Holm-Sidak test). (C) Total fentanyl consumption in female and male mice during quinine sessions. *p < 0.05 vs. 0-μM sessions (Dunnett’s test). (D-F) Fentanyl consumption from each bottle during quinine sessions. *p < 0.05, **p < 0.01 vs. 0-μM sessions (Dunnett’s test).