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. Author manuscript; available in PMC: 2022 Mar 1.

Published in final edited form as: J Psychiatr Res. 2021 Jan 19;135:248–255. doi: 10.1016/j.jpsychires.2021.01.021

Table 1. GF-mice show a transcriptional profile significantly correlated to that of post-mortem MDD subjects.

Spearman correlations, and p-values, comparing transcriptional changes observed to post-mortem cohorts of MDD subjects.

		Human MOD gene expression
	Experimental Group	Hippocampus (Duric et al., 2010)		Amygdala (Ding et al., 2015)		mPFC (Ding et al., 2015)
	Experimental Group	Rho	p	Rho	p	Rho	p
*Mouse gene expression*	GF	0.51^*	0.027^*	0.19	0.43	0.43	0.059^#
	Mono-Colonized	0.32	0.18	0.36	0.13	0.42	0.058^#
	SPF-Colonized	0.28	0.24	0.36	0.16	0.31	0.19

^*

p<0.05,

^#

p<0.1.