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Schematic of BRD4-NUT fusion protein. Arrows denote breakpoints. ET, extra-terminal domain; Bromo, bromodomain; TAD, transcriptional activation domain; NES, nuclear export signal; NLS, nuclear localization signal; CTD, C-terminal domain. TAD1 corresponds with “NUTF1C” fragment that binds p300 described in Reynoird N et al., 2010. Numbers denote amino acid numbers for the indicated domains.
