Table 1.
Baseline characteristics
| Parkinson onset | p values | |||
|---|---|---|---|---|
| YOPD (n = 272) | LOPD (n = 690) | |||
| Age at first onset | 46.3 ± 6.2 | 78.8 ± 4.5 | < 0.0001 | |
| Age at onset | 43.0 ± 6.1 | 75.9 ± 4.4 | < 0.0001 | |
| Weight | 81.9 ± 19.7 | 74.7 ± 14.4 | < 0.0001 | |
| Gender (%male) | 184 (67.6%) | 419 (60.7%) | 0.046 | |
| Living situation | At home | 271 (99.6%) | 645 (93.8%) | < 0.001 |
| Skilled care | 1 (0.4%) | 34 (4.9%) | ||
| Other | 0 (0.0%) | 9 (1.3%) | ||
| Regular care partner | No | 37 (13.6%) | 135 (19.6%) | < 0.001 |
| Spouse/Partner | 219 (80.5%) | 463 (67.2%) | ||
| Other Relative | 13 (4.8%) | 56 (8.1%) | ||
| Paid Caregiver | 1 (0.4%) | 29 (4.2%) | ||
| Other | 2 (0.7%) | 6 (0.9%) | ||
| Stand unaided | Yes | 2 (0.7%) | 49 (7.3%) | < 0.0001 |
| No | 268 (99.3%) | 622 (92.7%) | ||
| #Of years from symptom to onset | 3.4 ± 1.3 | 2.9 ± 1.4 | < 0.0001 | |
| #Of years from diagnosis to assessment | 2.0 ± 1.4 | 2.1 ± 1.4 | 0.710 | |
| H&Y stage | 1 | 92 (35.8%) | 89 (13.8%) | < 0.0001 |
| 2 | 154 (59.9%) | 340 (52.6%) | ||
| 3 | 10 (3.9%) | 173 (26.7%) | ||
| 4–5 | 1 (0.4%) | 45 (7.0%) | ||
| #Of symptomatic comorbidities | 0.2 ± 0.5 | 0.6 ± 0.9 | < 0.0001 | |
| Falls | None/rare | 225 (94.1%) | 531 (90.3%) | 0.074 |
| At least monthly | 14 (5.9%) | 57 (9.7%) | ||
| PDQ-39 total | 19.9 ± 15.2 | 21.0 ± 14.3 | 0.299 | |
| MCSI total | 13.9 ± 13.8 | 16.0 ± 13.9 | 0.137 | |
YOPD young-onset Parkinson’s disease, LOPD late-onset Parkinson’s disease, H&Y Hoehn and Yahr, PDQ-39 Parkinson’s disease questionnaire 39, MCSI modified caregiver strain index
Values stated as mean + − standard deviation or n (%)
The bold values indicate p < 0.05