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. 2021 Feb 27;11(2):42. doi: 10.1038/s41408-021-00434-2

Fig. 1. Association of single-nucleotide polymorphisms (SNPs) in CXCR3 ligand genes and serum chemokines with the incidence of severe chronic graft-versus-host disease (GVHD).

Fig. 1

A Carriers of the variant allele for CXCL9 polymorphism rs884304 (AA + AG) were associated with a significantly higher incidence of severe chronic GVHD in the training cohort. B Effects of the three candidate SNPs for genetic risk group B on the incidence of severe chronic GVHD after alloSCT. Genetic risk group B was based on rs3733236, rs4282209, and rs655328. C Association of severe chronic GVHD incidence with genetic risk groups A and B. D Association of serum CXCL9 levels with a cumulative incidence of severe chronic GVHD after alloSCT in the training cohort. E Association of day +28 CXCL9 serum levels with genetic risk groups A and B. n.s. not significant; *P ≤ 0.05; **P < 0.01; ***P < 0.001.