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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Surv Ophthalmol. 2020 Aug 29;66(2):213–230. doi: 10.1016/j.survophthal.2020.08.003

Table 3 —

Contrast sensitivity and impaired spatial frequency

Author(s) (year) No. of eyes (# subjects) Device (cpd) Range of spatial frequency (cpd) with decreased sensitivity (compared to the control group)

No DR NPDR PDR
Joltikov et al (2017)81 CN = 18 (n = 18)
No DR = 23 (n = 23)
Mild NPDR = 19 (n = 19)
Moderate NPDR = 15 (n = 15)
qCSF Procedure on AST Platform (1.5, 3, 6, 12, 18 cpd) 1.5, 3.0, 6.0, 12.0 1.5, 3.0, 6.0, 12.0, 18.0
Stem et al (2016)137 CN = 23 (n = 23)
No DR = 16 (n = 16)
Mild to Moderate NPDR = 14 (n = 14)
Pelli-Robson Chart (~ 1 cpd) ~1 ~1
Boynton et al (2015)27 CN = 15 (n = 15)
PDR = 15 (n = 15)
PRP = 30 (n = 30)
Pelli-Robson Chart (~ 1 cpd) ~1
Zhu et al (2015)154 CN = 158 (n = 158)
No DR = 141 (n = 141)
Functional Acuity Contrast test (FACT) Optec 6500 Device (1.5, 3, 6, 12, 18 cpd) 1.5, 3.0, 6.0, 12.0, 18.0
Andrade et al (2014)8 CN = 64 (n = 32)
DM = 49 (n = 27): 30
No DR, 13 NPDR, 6 PDR
Study Designed CS Software (0.2, 0.5, 0.8, 1, 2, 4, 6, 10, 15, 20, 30 cpd) 15.0, 30.0 0.5, 0.8, 1.0, 2.0, 4.0, 6.0, 10.0, 15.0, 20.0, 30.0 0.5, 0.8, 1.0, 2.0, 4.0, 6.0, 10.0, 15.0, 20.0, 30.0
Jackson et al (2012)77 CN = 18 (n = 18)
No DR = 23 (n = 23)
NPDR = 35 (n = 35)
Pelli-Robson Chart (~ 1 cpd) None ~1
Georgakopoulos et al (2011)57 CN = 90 (n = 45)
No DR = 120 (n = 60)
CSV-1000 Device (3, 6, 12, 18 cpd) 3.0, 6.0, 12.0, 18.0
Katz et al (2010)84 CN = 14 (n = 7)
No DR = 17 (n = 9)
Study Designed Platform Using Gabor Targets (photopic CS: 6, 9,12 cpd; mesopic CS: 3, 6, 9 cpd) 3.0 (Mesopic setting only)
Misra et al (2010)100 CN = 226 (n = 115)
DM = 382 (n = 205): 281
No DR, 93 NPDR, 8 PDR
Pelli-Robson Chart (~ 1 cpd) ~1 ~1 ~1
Di Leo et al (1992)46 CN = 60 (n = 30)
No DR = 48 (n = 24)
Study Designed CS (static and dynamic test: 0.6, 1.0, 1.4, 2.2, 4.8, 7.1, 9.6, 12.2 cpd) Dynamic:0.6, 1.0, 1.4, 2.2, 4.8, 7.1, 9.6; Static:1.0,1.4, 2.2, 7.1, 9.6
Trick et al (1988)139 CN 70 (n = 35)
No DR = 74 (n = 37)
Mild to Moderate NPDR = 40 (n = 20)
Vistech VCTS 6500 Distance Chart (1.5, 3.0, 6.0, 12.0, 18.0 cpd) None 6.0, 12.0

CS, contrast sensitivity; CN, control; DM, diabetes; DR, diabetic retinopathy; NPDR, nonproliferative diabetic retinopathy; PDR, proliferative diabetic retinopathy; PRP, pan-retinal photocoagulation; cpd, cycle per degree.