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. 2021 Feb 27;8:21. doi: 10.1186/s40658-021-00367-6

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Bar diagrams of intra-class correlation coefficient (ICC) values of RFs robustness to different intensity rescale factors (RR and AR60) when no threshold was applied for different operators and semi-automatic algorithm. Bars in blue show the median ICC between different segmentations, applying no threshold. Range error bars (in black) encompass the lowest and highest values for different operators. b Boxplot of COV^L for different intensity rescale factors (RR and AR60), applying no threshold, for the first operator (results superposable for the other operators). TLG (total lesion glycolysis) conventional parameter in our study corresponds to the TLSRE (total lesion somatostatin receptor expression)