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. 2021 Jan 22;11(8):3580–3594. doi: 10.7150/thno.55441

Figure 6.

Figure 6

In vivo antitumor efficacy of CV@CaP in combination with radiotherapy and phototherapy. (A) Experimental schematic of CV@CaP-mediated enhanced radio-phototherapy to inhibit tumor growth in the orthotopic 4T1 breast tumor model. (B) Representative photographs of the 4T1 tumor-bearing mice (black dashed circles: the tumor sites) at 18 days after different treatments (n =5). Treatments: 1) Control; 2) CV@CaP alone; 3) Laser alone (1.0 W/cm, 3 min); 4) RT alone (6 Gy); 5) RT + Laser; 6) CV@CaP + Laser; 7) CV@CaP + RT; and 8) CV@CaP + RT + Laser. (C) Tumor growth curves of mice in different groups (D) Photograph of the dissected tumors at 18 days in different groups. ***p < 0.001.