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. 2021 Feb 15;11(8):3964–3980. doi: 10.7150/thno.54824

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This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.

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DR4 expression, like pathological grade and clinical stage, is significantly associated with poor survival of lung adenocarcinoma patients. A, Analysis of the association between DR4 expression and clinico-pathological features of lung adenocarcinomas (n = 242). Chi-square test was used to calculate statistical significance. LNM, lymph node metastasis. B, Representative images of DR4 staining. C, Kaplan-Meier survival analyses of the impact of DR4 expression, pathological grade and clinical stage on the survival of lung adenocarcinoma patients.