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. 2021 Jan 27;11(8):3710–3724. doi: 10.7150/thno.53828

Figure 3.

Figure 3

(A) Hemolysis test of PM, PMP, Py-TPE@PM, Py-TPE@PMP, Py-TPE/siRNA@PM, Py-TPE/siRNA@PMP, PBS and water. (B) The pharmacokinetics of Py-TPE/siRNA@PMP in vivo. (C) In situ real-time imaging of Py-TPE/siRNA@PMP NPs in SKOV-3/PTX cell tumor bearing mice. The area within the white dotted line was the location of the tumor. (D) The Py-TPE fluorescence intensity of tumor area was quantitatively analyzed. (E) The bio-distribution of Py-TPE/siRNA@PMP in vivo. Ex =430 nm, Em =600 nm. (F) Quantification of the bio-distribution of Py-TPE/siRNA@PMP in vivo. (G) The images of Py-TPE/siRNA@PMP in tumor or organ was detected by CLSM.