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Administration of B. breve A1 restored the decreased dendritic spine density in the CA1 region of the hippocampus. (A) Representative images of spines. Scale bar = 2 µm. (B) The dendritic spine density per 10 µm decreased in PD mice. Administration of B. breve A1 prevented the reduction of spine density in PD mice. Data are expressed as the mean ± SEM; n = 4 per group. * p < 0.01 vs. Control + Saline and † p < 0.05: between MPTP + Saline and MPTP + B. breve A1.
