A: |
adenine |
A549: |
human adenocarcinoma alveolar basal epithelial cells |
ATM: |
ataxia telangiectasia mutated |
ATR: |
ataxia and Rad3-related |
Bax: |
BCL2-associated X protein |
BCL2: |
B-cell lymphoma 2 gene |
BG4: |
anti-G-quadruplex recombinant antibody |
BRCA: |
breast cancer susceptibility protein-encoding gene |
C: |
cytocine |
CA46: |
Burkitt’s lymphoma cancer cells |
CDK6: |
cyclin-dependent kinase 6 |
CHK1: |
checkpoint kinase 1 |
CNBP: |
cellular nucleic acid-binding protein |
Cox-2: |
cyclooxygenase-2 |
CST: |
cellular multiprotein complex, composed of proteins CTC1 (copy telomere complex component 1), STN1 (telomere end-binding and capping protein) and TEN1 (telomere length regulation protein) in mammals |
3D: |
three-dimensional |
DOG1: |
helicase ATP-binding domain-containing protein |
DNA: |
deoxyribonucleic acid |
DNA pol: |
DNA polymerase |
dsDNA: |
double-stranded DNA |
EWS: |
Ewing’s sarcoma protein |
FANCJ: |
Fanconi anemia group J protein (helicase) |
FUS: |
fused in sarcoma, RNA-binding protein |
G: |
guanine |
GAPDH: |
glyceraldehyde 3-phosphate dehydrogenase |
GIST: |
gastrointestinal stromal tumor |
GSC: |
glioblastoma/glioma stem cells |
GTP: |
guanosine triphosphate |
HCT15: |
colorectal adenocarcinoma cell line |
HCT116: |
human colon cancer cell line with mutation in codon 13 of the KRAS proto-oncogene |
HEK293: |
human embryonic kidney cell line |
HeLa: |
immortal cervical human cell line named after the original donor Henrietta Lacks |
Hep-2: |
human laryngeal squamous carcinoma cells |
HIFA: |
hypoxia inducible factor A |
HR: |
homologous recombination |
HRAS: |
Harvey rat sarcoma viral oncogene homolog |
HSP90: |
heat shock protein 90 |
hTERT: |
human telomerase reverse transcriptase gene |
IC50: |
half maximal inhibitory concentration |
IR: |
ionizing radiation |
Jurkat: |
immortalized line of human T lymphocyte cells |
KIT: |
proto-oncogene encoding for receptor tyrosine kinase KIT |
KRAS: |
Kirsten rat sarcoma virus proto-oncogene |
MAPK: |
mitogen-activated protein kinase |
Max: |
MYC-associated factor X |
MCF-7: |
human breast cancer cell line |
Mia PaCa 2: |
human pancreatic cancer cell line |
mRNA: |
messenger RNA |
mTOR: |
mammalian target of rapamycin |
MYB: |
Avian virus myeloblastosis gene homolog, proto-oncogene |
MYC: |
Avian virus myelocytomatosis gene homolog, proto-oncogene |
NCT: |
United States patent number |
NHE III1: |
nuclease hypersensitive element III1
|
NMR: |
nuclear magnetic resonance |
NRAS: |
neuroblastoma rat sarcoma viral gene homolog |
NSGC: |
non-stem glioma cells |
p21: |
cyclin-dependent kinase inhibitor 1 |
p53: |
tumor suppressor protein 53 |
PANC-1: |
human pancreatic cancer cell line isolated from ductal pancreatic carcinoma |
PARP: |
poly(ADP-ribose) polymerase |
PCR: |
polymerase chain reaction |
PDAC: |
pancreatic ductal adenocarcinoma |
PDGFA: |
platelet-derived growth factor subunit A |
PIF1: |
5’-to-3’ DNA helicase |
POT1: |
protection-of-telomeres protein 1 |
RAD51: |
repair-of-DNA protein-encoding gene |
Rap1: |
Ras-proximate protein1 |
Rb1: |
retinoblastoma gene |
rDNA: |
ribosomal DNA |
RET: |
rearranged-during-transfection proto-oncogene |
RNA: |
ribonucleic acid |
RNA pol: |
RNA polymerase |
RNA-seq: |
RNA sequencing |
rRNA: |
ribosomal RNA |
RTEL1: |
regulator of telomere elongation helicase 1 |
Saos-2: |
human osteosarcoma cancer cell line |
SL1: |
selective factor 1 |
SP1: |
specificity protein 1 |
SPR: |
surface plasmon resonance |
ssDNA: |
single-stranded DNA |
SW620: |
human colon adenocarcinoma cell line |
T: |
thymine |
TERRA: |
telomeric repeat-containing RNA |
TF: |
transcription factor |
TPP1: |
tripeptidyl-peptidase 1 |
TRF2: |
telomeric repeat-binding factor 2 |
UTR: |
untranslated regions |
VEGF: |
vascular endothelial growth factor gene |