Table 5.
Fatty Acid | Control | HTN | CHD | Type 2 DM | Diabetic Nephropathy |
---|---|---|---|---|---|
16:0 | 25.9 ± 3.0 | 29.3 ± 2.7 * | 27.8 ± 3.5 | 26.6 ± 5.2 | 26.8 ± 2.7 |
18:0 | 20.9 ± 3.6 | 23.2 ± 4.9 * | 18:0 ± 10.7 | 14.6 ± 4.1 | 11.6 ± 3.6 * |
18:1 n−9 | 13.0 ± 2.3 | 12.1 ± 1.5 | 11.5 ± 3.1 | 12.0 ± 2.6 | 14.5 ± 3.1 |
18:2 n−6 (LA) | 18.6 ± 3.1 | 14.5 ± 3.1 * | 17.8 ± 5.0 | 13.9 ± 5.3 | 15.1 ± 3.1 |
18:3 n−6 (GLA) | 0.14 ± 0.1 | 0.4 ± 0.3 * | 0.1 ± 0.1 * | 0.2 ± 0.3 | 0.1 ± 0.2 |
20:3 n−6 (DGLA) | 3.4 ± 1.0 | 3.1 ± 0.9 | 2.7 ± 1.1 | 1.7 ± 1.0 * | 2.0 ± 0.8 * |
20:4 n−6 (AA) | 9.4 ± 1.8 | 7.8 ± 2.0 * | 7.0 ± 2.1 * | 4.6 ± 1.8 * | 6.6 ± 2.6 * |
22:5 n−6 | 0.7 ± 0.4 | 0.4 ± 0.4 * | 1.0 ± 0.9 | 2.1 ± 0.6 * | 1.3 ± 0.5 * |
18:3 n−6/18:2 n−6 | 0.008 | 0.026 | 0.005 | 0.017 | 0.008 |
20:4 n−6/18:2 n−6 | 0.51 | 0.54 | 0.39 | 0.33 | 0.43 |
20:4 n−6/20:3−6 | 2.8 | 2.53 | 2.59 | 2.8 | 3.3 |
18:3 n−3 (ALA) | 0.2 ± 0.1 | 0.4 ± 0.2 * | 0.3 ± 0.5 | 0.1 ± 0.2 * | 0.1 ± 0.1 * |
20:5 n−3 (EPA) | 0.4 ± 0.4 | 0.6 ± 0.6 | 0.1 ± 0.2 * | 0.3 ± 0.3 | 0.2 ± 0.3 |
22:5 n−3 | 0.5 ± 0.2 | 0.4 ± 0.5 | 0.3 ± 0.3 * | 1.6 ± 1.3 | 1.7 ± 1.1 |
22:6 n−3 (DHA) | 1.4 ± 0.5 | 1.2 ± 0.6 | 0.8 ± 0.4 * | 0.5 ± 0.4 * | 0.5 ± 0.3 * |
20:5 n−3/18:3 n−3 | 1.8 | 1.39 | 0.41 | 3.2 | 4.0 |
All values are expressed as mean ± S. D. * p < 0.05 compared to control. This data is taken from [155].