Table 5.
Results of regression analysis for other cardiovascular outcomes (exposed vs unexposed).
| Outcomes | Exposed vs. Unexposed | |||
|---|---|---|---|---|
| Crude Mean Diff (95% CI) | p-Value | Adj Mean Diff * (95% CI) | p-Value | |
| Serum Biomarkers | ||||
| Log NTproBNP | 0.06 (−0.14, 0.27) | 0.550 | 0.07 (−0.11, 0.25) | 0.451 |
| Log Troponin | 0.13 (0.00, 0.27) | 0.046 | 0.09 (−0.03, 0.21) | 0.124 |
| Total cholesterol | −0.28 (−0.46, −0.09) | 0.004 | −0.14 (−0.30, 0.01) | 0.070 |
| HDL | −0.04 (−0.12, 0.04) | 0.286 | 0.02 (−0.04, 0.08) | 0.539 |
| LDL | −0.28 (−0.45, −0.10) | 0.002 | −0.15 (−0.30, −0.01) | 0.038 |
| Triglycerides | 0.11 (−0.08, 0.31) | 0.257 | 0.00 (−0.18, 0.19) | 0.975 |
| Peak FMD (%) ‡ | 0.08 (−0.48, 0.64) | 0.773 | −0.01 (−0.54, 0.52) | 0.967 |
| Blood pressure | ||||
| Systolic BP (mmHg) | −3.28 (−6.68, 0.13) | 0.059 | −3.75 (−7.23, −0.26) | 0.035 |
| Diastolic BP (mmHg) | −2.07 (−4.21, 0.08) | 0.059 | −1.74 (−3.80, 0.31) | 0.097 |
| Crude OR (95% CI) | p-value | Adj OR † (95% CI) | p-value | |
| ECG | ||||
| Atrial Fibrillation | 0.68 (0.31, 1.52) | 0.350 | 0.41 (0.14, 1.16) | 0.094 |
| Other rhythm abnormality | 0.75 (0.36, 1.56) | 0.442 | 0.50 (0.20, 1.23) | 0.130 |
| Evidence of underlying IHD | 1.55 (0.89, 2.69) | 0.122 | 1.52 (0.83, 2.78) | 0.177 |
* = Adjusted for age, gender, employment, education, history of cardiovascular diseases, body mass index, smoking and drinking status, physical activity, HbA1c, systolic blood pressure (not including analysis of systolic and diastolic blood pressure), taking lipid-lowering therapy and anti-inflammatory/immunosuppressants; † = Adjusted for age, gender, employment, education, body mass index, smoking and drinking status, physical activity, HbA1c, taking lipid-lowering therapy and taking anti-inflammatory/immunosuppressants; ‡ = Includes 379 valid FMD tests for 220 Morwell and 159 Sale participants. Eight low quality test results were excluded. Abbreviations: Diff = difference; Adj Mean Diff = adjusted mean difference; NTproBNP = N-terminal pro B-type natriuretic peptide; HDL = high-density lipoprotein; LDL = low-density lipoprotein; BP = blood pressure; Adj OR = adjusted Odds Ratio; ECG = electrocardiograph; IHD = ischaemic heart disease.