Plg-RKT deletion alters the ECM in lactating mammary glands. Abdominal mammary glands were harvested from Plg-RKT+/+ and Plg-RKT−/− female mice two days postpartum and stained with anti-fibrin(ogen) antibody (the curved yellow arrow labels represent fibrin deposition in alveoli; the curved orange arrow labels represent fibrin deposition in dilated ducts; the straight yellow arrows labels represent fibrin deposition in adipose tissue) or non-immune rabbit IgG control. This research was originally published in Miles, L.A.; Baik, N.; Bai, H.; Makarenkova, H.P.; Kiosses, W.B.; Krajewski, S.; Castellino, F.J.; Valenzuela, A.; Varki, N.M.; Mueller, B.M.; Parmer, R.J. The plasminogen receptor, Plg-RKT, is essential for mammary lobuloalveolar development and lactation. J. Thromb. Haemost.
2018, 16, 919–932. [83] Reprinted with permission from John Wiley and Sons.