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. 2021 Feb 5;22(4):1616. doi: 10.3390/ijms22041616

Table 1.

Effect of localization on the cumulative release of PINP, PRO-C3, PRO-C6, and C3M biomarkers from fibroblasts into the media over 8 days of culture shown as ng/well 1.

Collagen Biomarker Proximal Distal p-Value 2
PINP 1580 (855–2290) 2620 (655–4190) 0.0854
PRO-C3 3.7 (2.0–4.9) 3.7 (1.5–4.3) 0.184
PRO-C6 4.2 (2.3–6.2) 6.7 (3.2–14.2) 0.00497
C3M 2.0 (1.7–2.8) 2.9 (1.4–3.9) 0.125

1 Median (interquartile range), n = 19. 2 Wilcoxon signed-rank test.