Table 2.

Effect of sex on cumulative release of PINP, PRO-C3, PRO-C6, and C3M biomarkers by colorectal fibroblasts (CoReFs) into the media over 8 days of culture shown as ng/well. ^1.

Collagen Biomarker	Males	Females	p-Value 2
PINP	1470 (716–3460)	2650 (2090–3620)	0.206
PRO-C3	4.0 (2.8–4.9)	3.0 (1.8–4.4)	0.206
PRO-C6	5.0 (4.1–6.0)	6.7 (2.4–11.4)	0.778
C3M	2.2 (1.6–2.6)	2.9 (2.3–3.5)	0.174

¹ Median (interquartile range). ² Mann–Whitney U test.