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. 2021 Feb 5;22(4):1616. doi: 10.3390/ijms22041616

Table 3.

Effect of TGF-β1 treatment of the CoReFs on cumulative release of PINP, PRO-C3, PRO-C6, and C3M biomarkers into the media over 8 days of culture shown as ng/well 1.

Collagen Biomarker Control TGF-β1 p-Value 2
PINP 2520 (2040–3340) 4550 (3310–6660) 0.00222
PRO-C3 3.4 (2.6–4.6) 3.9 (2.2–4.8) 0.666
PRO-C6 5.4 (3.8–10.3) 9.3 (6.6–12.1) 0.00221
C3M 2.3 (1.7–2.9) 2.3 (1.6–2.8) 0.593

1 Median (interquartile range), n = 12. 2 Wilcoxon signed-rank test.