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Plasma ALZ sulfoxide concentration profiles after oral administration of crystalline ALZ and its ASDs in beagle dogs at a dose of 10 mg/kg (n = 3). Formulations were administered as capsules unless otherwise noted as suspension. Symbols: crystalline ALZ (◆), PVPVA ASD (■), HPMCAS ASD (▲), HPMCAS ASD (suspension) (△), Eudragit ASD (●).
