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Natural-polysaccharide-based pharmacology therapy for OA.
| Compound (Source) |
Category | Therapeutic Target | Treatment | Ref. |
|---|---|---|---|---|
| Achyranthes bidentata extracts | Various polysaccharides | Induces chondrocyte proliferation, Wnt/β-catenin pathway activation, and inhibits apoptosis via MAPK/Akt signaling. | Anti-apoptotic effect and induces proliferation. | [199,200] |
| Promotes bone formation and inhibits osteoclastogenesis via the inhibition of RANK. | Bone formation. | [201,202,203] |
