Table 1.
Gene Ontology terms enriched in 402 human HTT-interactors.
| Term | Count | p-Value |
|---|---|---|
| protein binding | 315 | 2.28 × 10−33 |
| myelin sheath | 41 | 6.12 × 10−30 |
| cytosol | 153 | 1.36 × 10−20 |
| mitochondrion | 86 | 4.07 × 10−18 |
| cytoplasm | 179 | 5.81 × 10−11 |
| membrane | 99 | 1.32E × 10−10 |
| extracellular exosome | 116 | 1.82 × 10−10 |
| nucleoplasm | 114 | 5.51 × 10−10 |
| ubiquitin protein ligase binding | 31 | 1.93 × 10−9 |
| identical protein binding | 50 | 1.29 × 10−8 |
| protein C-terminus binding | 23 | 1.02 × 10−7 |
| protein complex | 33 | 1.27 × 10−7 |
| protein complex binding | 24 | 1.94 × 10−7 |
| autophagosome | 14 | 3.48 × 10−7 |
| protein stabilization | 20 | 4.17 × 10−7 |
| cell–cell adherens junction | 27 | 3.10 × 10−6 |
| transcription factor binding | 26 | 4.79 × 10−6 |
| cadherin binding involved in cell–cell adhesion | 26 | 7.30 × 10−6 |
| mitochondrial inner membrane | 31 | 1.02 × 10−5 |
| macroautophagy | 14 | 2.71 × 10−5 |