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. 2021 Feb 9;22(4):1730. doi: 10.3390/ijms22041730

Table 4.

The summary of literature research for therapy for PTSD related to thalamus.

Discussion Reference Number
Trauma-exposed control showed depleted connectivity between thalamus and postcentral gyrus [81]
Enhanced connectivity between the centromedial amygdala and pulvinar, and depletion between the basolateral amygdala and SC [82]
Amygdala−thalamus connection enhanced during recovery process [83]
EMDR
Contribution of mediodorsal thalamus to fear processing [64,84,85,86]
Animal EMDR model provides sustained activation between SC and mediodorsal thalamus with fear reducing effects [87]
EMDR reduced gray matter volume in the left thalamus [88]
Hyperbaric Oxygen Therapy (HBOT)
HBOT enhances FA in the thalamic radiation, left thalamus, and insula, with improved PTSD scores [39]
Oxytocin Administration
Enhanced activity in the left thalamus during tasks both in PTSD and controls [89]
Oxytocin administration decreased connectivity between left thalamus and amygdala in men with PTSD and traumatized controls, but increased connectivity in woman with PTSD [89]