Table 1.
Description of the LIFE (Leipzig Research Centre for Civilization Diseases) Child cohort stratified by age intervals.
| Age (Years) | 0–1 (n = 453) |
1–5 (n = 868) |
6–12 (n = 1982) |
13–18 (n = 1175) |
Total (n = 4478) |
|---|---|---|---|---|---|
| Sex Category | |||||
| Male | 243 (53.6%) | 450 (51.8%) | 1046 (52.8%) | 560 (47.7%) | 2299 (51.3%) |
| Female | 210 (46.4%) | 418 (48.2%) | 936 (47.2%) | 615 (52.3%) | 2179 (48.7%) |
| Cobalamin (pmol/L) | |||||
| Mean (SD) | 322 (161) | 467 (165) | 430 (145) | 331 (122) | 401 (155) |
| Median (Min, Max) | 279 (86.4, 1050) | 446 (131, 1200) | 408 (135, 1350) | 308 (95.1, 874) | 377 (86.4, 1350) |
| Missing | 92 (20.3%) | 66 (7.6%) | 52 (2.6%) | 39 (3.3%) | 249 (5.6%) |
| Folate (nmol/L) | |||||
| Mean (SD) | 40.3 (6.76) | 29.8 (8.60) | 24.8 (7.62) | 19.3 (6.88) | 25.6 (9.45) |
| Median (Min, Max) | 44.2 (17.8, 45.4) | 28.7 (10.4, 45.4) | 23.8 (8.34, 45.4) | 18.2 (5.87, 45.4) | 23.9 (5.87, 45.4) |
| Missing | 103 (22.7%) | 81 (9.3%) | 70 (3.5%) | 53 (4.5%) | 307 (6.9%) |
| BMI-SDS | |||||
| Underweight | 38 (8.4%) | 44 (5.1%) | 164 (8.3%) | 83 (7.1%) | 329 (7.3%) |
| Normal weight | 380 (83.9%) | 749 (86.3%) | 1468 (74.1%) | 833 (70.9%) | 3430 (76.6%) |
| Overweight | 32 (7.1%) | 44 (5.1%) | 142 (7.2%) | 106 (9.0%) | 324 (7.2%) |
| Obese | 2 (0.4%) | 14 (1.6%) | 197 (9.9%) | 143 (12.2%) | 356 (7.9%) |
| Missing | 1 (0.2%) | 17 (2.0%) | 11 (0.6%) | 10 (0.9%) | 39 (0.9%) |
| SES (WI) | |||||
| Low SES | 39 (8.6%) | 71 (8.2%) | 199 (10.0%) | 152 (12.9%) | 461 (10.3%) |
| Middle SES | 258 (57.0%) | 500 (57.6%) | 1136 (57.3%) | 668 (56.9%) | 2562 (57.2%) |
| High SES | 130 (28.7%) | 270 (31.1%) | 564 (28.5%) | 259 (22.0%) | 1223 (27.3%) |
| Missing | 26 (5.7%) | 27 (3.1%) | 83 (4.2%) | 96 (8.2%) | 232 (5.2%) |
BMI-SDS groups: underweight: BMI-SDS < −1.28; normal weight: BMI-SDS −1.28 to <1.28; overweight: BMI-SDS > 1.28 to 1.88; obese: BMI-SDS > 1.88. SES groups: low: WI 3–8.4; middle: WI 8.5–15; high: 15.5–21. SD = standard deviation; Min = lowest value; Max = highest value; n = number of observations; BMI-SDS = body mass index standard deviation score; SES = socioeconomic status; WI = Winkler Index.