Figure 5.
Entheseal soft tissue (EST) mesenchymal stem cells (MSCs) (n = 4) undergoing 21-day adipogenesis ± IL-17A (50 ng/mL). Transcripts relating to adipogenesis and vesicle fusion (paired t-tests) showing significant downregulation by the stimulation of IL-17A. Transcripts relating to MSC stromal support (CXCL12) and inflammatory cell migration (CCL20) showing significant upregulation by the stimulation of IL-17A compared to a control adipogenic media. * = p < 0.05, ** = p < 0.01, *** = p < 0.001, and **** = p < 0.0001.