Figure 1.

Aldosterone signaling pathway most significantly affected by oregano with 19 genes. Oregano significantly inhibited pathways included, IGF-1 Signaling, PI3K Signaling in B Lymphocytes, CREB Signaling in Neurons, Gαq Signaling, Thrombin Signaling, Production of Nitric Oxide and Reactive Oxygen Species in Macrophages, Synaptic Long Term Depression, IL-3 Signaling, LPS-stimulated MAPK Signaling, CCR3 Signaling in Eosinophils, α-Adrenergic Signaling, Growth Hormone Signaling, Melatonin Signaling, Pancreatic Adenocarcinoma Signaling, Apelin Endothelial Signaling Pathway, Th1 Pathway, IL-6 Signaling, with full pathway list and statistics provided in Table S4. Activated pathways were Colanic Acid Building Blocks Biosynthesis, BAG2 Signaling Pathway, LPS/IL-1 Mediated Inhibition of RXR Function, Antioxidant Action of Vitamin C, and PTEN Signaling, as in Table S4.