Table 3.
Absolute abundance values indicating the faecal abundance of bacteria in various taxonomic levels at T0 and T1 among the control and intervention participants.
| Control Group (n = 20) | Intervention Group (n = 19) | |||
|---|---|---|---|---|
| T0 (Baseline) | T1 (24 Weeks) | T0 (Baseline) | T1 (24 Weeks) | |
| Absolute abundance (number of reads) | ||||
| Phylum | ||||
| Firmicutes | 19,211 (14,696, 21,670) | 17,224 (14,512, 19,996) | 15,375 (12,747, 16,761) | 16,209 (13,531, 18,752) |
| Bacteroidetes | 16,396 (15,074, 19,594) | 17,674 (14,340, 20,421) | 18,987 (14,466, 22,206) | 19,812 (17,450, 22,988) |
| Proteobacteria | 2703 (1904, 3589) | 3568 (2386, 5157) | 2526 (1926, 5051) | 3954 (2040, 6645) |
| Actinobacteria | 229 (153, 560) | 366 (182, 1018) | 199 (141, 307) | 876 (358, 1336) |
| Fusobacteria | 61 (33, 200) | 52 (15, 136) | 99 (23, 953) | 54 (24, 1613) |
| Firmicutes/Bacteroidetes ratio | 1.190 (0.866, 1.588) | 1.018 (0.816, 1.239) | 0.794 (0.639, 0.979) | 0.775 (0.656, 0.989) |
| Class | ||||
| Bacteroidia | 16,396 (15,074, 19,594) | 17,674 (14,336, 20,420) | 18,987 (14,466, 22,206) | 19,801 (17,450, 22,988) |
| Clostridia | 16,714 (12,641, 20,710) | 15,230 (12,924, 18,568) | 12,133 (10,841, 15,110) | 13,532 (10,966, 15,929) |
| Negativicutes | 1190 (602, 1510) | 1489 (946, 1866) | 834 (634, 1415) | 1652 (971, 2117) |
| Bacilli | 82 (40, 292) | 79 (28, 134) | 108 (43, 357) | 148 (95, 196) |
| Gammaproteobacteria | 2278 (1298, 2863) | 2436 (1836, 4682) | 2254 (1602, 4908) | 2879 (1976, 6249) |
| Order | ||||
| Bacteroidales | 16,394 (15,073, 19,583) | 17,674 (14,230, 20,346) | 18,986 (14,448, 22,206) | 19,699 (17,396, 22,988) |
| Clostridiales | 16,711 (12,640, 20,708) | 15,228 (12,924, 18,567) | 12,130 (10,841, 15,110) | 13,531 (10,966, 15,929) |
| Selenomonadales | 1190 (602, 1510) | 1489 (946, 1866) | 834 (634, 1415) | 1652 (971, 2117) |
| Lactobacillales | 38 (24, 74) | 36 (26, 76) | 36 (19, 53) | 73 (25, 99) |
| Enterobacteriales | 423 (226, 1190) | 976 (557, 3221) | 337 (117, 965) | 454 (216, 865) |
| Family | ||||
| Bacteroidaceae | 13,433 (8114, 16,306) | 12,500 (8170, 17,482) | 10,808 (5397, 15,592) | 12,226 (4698, 15,899) |
| Prevotellaceae | 602 (366, 1484) | 548 (456, 1750) | 1021 (548, 11,807) | 971 (553, 10,564) |
| Clostridiaceae_1 | 50 (30, 83) | 22 (12, 36) | 43 (18, 136) | 33 (15, 59) |
| Lachnospiraceae | 6294 (5660, 8950) | 6947 (5388, 9041) | 6937 (5385, 8577) | 6638 (4647, 8269) |
| Veillonellaceae | 694 (260, 1266) | 812 (340, 1474) | 306 (168, 1075) | 542 (219, 1874) |
| Genus | ||||
| Bacteroides | 13,433 (8114, 16,306) | 12,500 (8170, 17,482) | 10,808 (5397, 15,592) | 12,226 (4698, 15,899) |
| Prevotella_9 | 400 (227, 1000) | 441 (304, 1031) | 472 (369, 9805) | 491 (310, 9629) |
| Clostridium_sensu_stricto_1 | 50 (30, 83) | 22 (12, 34) | 43 (18, 136) | 32 (15, 51) |
| Veillonella | 10 (7, 30) | 41 (14, 95) | 11 (3, 35) | 18 (12, 91) |
| Lactobacillus | 0 (0, 18) | 1 (0, 18) | 0 (0, 31) | 36 (0, 62) |
| Bifidobacterium | 122 (70, 198) | 129 (63, 197) | 63 (30, 124) | 162 (93, 395) |
| Faecalibacterium | 2734 (1470, 3684) | 2270 (1780, 3014) | 2410 (1307, 3467) | 2326 (728, 3324) |
| Escherichia-Shigella | 206 (122, 416) | 421 (273, 1354) | 83 (64, 283) | 206 (133, 322) |
| Blautia | 142 (102, 192) | 108 (87, 204) | 133 (100, 202) | 113 (74, 199) |
| Roseburia | 498 (290, 1160) | 514 (334, 926) | 614 (292, 941) | 605 (371, 1638) |
| Fusobacterium | 52 (30, 200) | 52 (15, 136) | 99 (17, 953) | 54 (24, 1613) |
| Ruminococcus_1 | 224 (133, 529) | 216 (161, 346) | 183 (78, 345) | 174 (84, 262) |
| Ruminococcus_2 | 384 (238, 619) | 508 (282, 762) | 351 (145, 631) | 506 (197, 709) |
| Species | ||||
| Faecalibacterium prausnitzii | 5 (2, 8) | 6 (3, 10) | 2 (0, 6) | 4 (1, 7) |
| Bifidobacterium longum | 18 (5, 32) | 19 (12, 36) | 8 (3, 29) | 20 (12, 38) |
| Clostridium butyricum | 12 (0, 42) | 0 (0, 2) | 0 (0, 38) | 0 (0, 3) |
| Bacteroides fragilis | 45 (17, 192) | 68 (26, 223) | 42 (15, 102) | 68 (23, 126) |
Data are presented as median (inter-quartile range).