Table 4.
Differences in RPC vessel density among patients and controls.
| MS+ON vs. Controls | MS−ON vs. Controls | NMOSD+ON vs. Controls | NMOSD−ON vs. Controls | |||||
|---|---|---|---|---|---|---|---|---|
| RPC (%) | β (SE) | p-Value | β (SE) | p-Value | β (SE) | p-Value | β (SE) | p-Value |
| average | −6.209 (1.042) | <0.001 | −3.104 (0.711) | <0.001 | −12.172 (3.272) | <0.001 | −2.372 (0.739) | 0.001 |
| ST | −6.548 (1.576) | <0.001 | −2.839 (0.859) | <0.001 | −13.862 (4.407) | 0.002 | −3.713 (0.925) | <0.001 |
| SN | −3.466 (1.458) | 0.017 | −1.207 (1.116) | 0.279 | −13.171 (3.701) | <0.001 | −0.792 (1.235) | 0.521 |
| NS | −3.587 (1.223) | 0.003 | −0.925 (1.014) | 0.361 | −10.439 (2.991) | <0.001 | −1.537 (1.089) | 0.158 |
| NI | −5.668 (1.334) | <0.001 | −2.585 (0.967) | 0.007 | −8.474 (3.227) | 0.009 | −3.458 (1.587) | 0.029 |
| IN | −4.557 (1.392) | 0.001 | −3.820 (1.050) | <0.001 | −13.709 (3.694) | <0.001 | −1.661 (1.132) | 0.142 |
| IT | −5.824 (1.403) | <0.001 | −3.843 (1.001) | <0.001 | −16.532 (4.808) | <0.001 | −3.724 (1.251) | 0.003 |
| TI | −10.603 (1.600) | <0.001 | −5.770 (1.031) | <0.001 | −11.034 (2.691) | <0.001 | −2.390 (1.859) | 0.198 |
| TS | −9.955 (1.700) | <0.001 | −4.653 (0.939) | <0.001 | −12.339 (2.626) | <0.001 | −2.413 (1.158) | 0.037 |
| MS+ON vs. MS−ON | NMOSD+ON vs. NMOSD−ON | NMOSD+ON vs. MS+ON | NMOSD−ON vs. MS−ON | |||||
| RPC (%) | β (SE) | p - Value | β (SE) | p - Value | β (SE) | p - Value | β (SE) | p - Value |
| average | −3.106 (0.906) | <0.001 | −9.800 (3.266) | 0.003 | −5.963 (3.364) | 0.076 | 0.731 (0.756) | 0.333 |
| ST | −3.709 (1.551) | 0.017 | −10.148 (4.356) | 0.020 | −7.313 (4.628) | 0.114 | −0.874 (1.055) | 0.408 |
| SN | −2.259 (1.367) | 0.098 | −12.380 (3.761) | <0.001 | −9.706 (3.854) | 0.012 | 0.415 (1.342) | 0.757 |
| NS | −2.662 (1.092) | 0.015 | −8.902 (2.960) | 0.003 | −6.851 (3.055) | 0.025 | −0.611 (1.051) | 0.561 |
| NI | −3.083 (1.173) | 0.009 | −5.016 (3.440) | 0.145 | −2.806 (3.362) | 0.404 | −0.873 (1.601) | 0.586 |
| IN | −0.738 (1.128) | 0.513 | −12.047 (3.670) | 0.001 | −9.151 (3.780) | 0.015 | 2.159 (1.044) | 0.039 |
| IT | −1.981 (1.402) | 0.158 | −12.808 (4.659) | 0.006 | −10.708 (4.925) | 0.030 | 0.119 (1.317) | 0.928 |
| TI | −4.833 (1.444) | <0.001 | −8.644 (3.206) | 0.007 | −0.431 (2.976) | 0.885 | 3.380 (1.890) | 0.074 |
| TS | −5.302 (1.508) | <0.001 | −9.926 (2.757) | <0.001 | −2.384 (2.967) | 0.422 | 2.240 (1.116) | 0.045 |
β = regression coefficient; IN = inferior nasal; IT = inferior temporal; MS = multiple sclerosis; NI = nasal inferior; NMOSD = neuromyelitis optica spectrum disorder; NS = nasal superior; ON = optic neuritis; RPC = radial peripapillary capillaries; SE= standard error; SN = superior nasal; ST = superior temporal; TI = temporal inferior; TS = temporal superior.