Table 3.

¹H NMR data for and 1–4.

Complex	ppm, Hz (DMSO-d6)
Carvedilol	11.28 (s, 1H, NH), 8.29 (d, J = 8.1 Hz, 1H, Ar), 7.50 (d, J = 8.1 Hz, 1H, Ar), 7.38 (t, J = 8.1 Hz, 1H, Ar), 7.35 (d, J = 8.1 Hz, 1H, Ar), 7.31 (d, J = 8.1 Hz, 1H, Ar), 7.18 (t, J = 8.1 Hz, 1H, Ar), 7.12 (d, J = 8.1 Hz, 1H, Ar), 6.95–6.71 (m, 4H, Ar), 5.21 (s, exch., 1H, NH), 4.23–4.16 (m, 4H, OH, CH2 and CH), 4.03 (t, J = 7.1 Hz, 2H, CH2), 3.75 (s, 3H, OMe), 2.97 (m, 2H, CH2), 2.01 (s, 1H, NH)
1	11.28 (s, 1H, NH), 8.28 (d, J = 8.0 Hz, 1H, Ar), 7.90–7.82 (m, 5H, Ar), 7.49–7.32 (m, 10H, Ar), 7.28–7.11 (m, 4H, Ar), 6.98–6.86 (m, 5H, Ar), 6.72 (d, J = 8.0 Hz, 1H, Ar), 4.25–4.22 (m, 3H, CH2 and CH), 4.07–4.02 (m, 2H, CH2), 3.75 (s, 3H, OMe), 3.00–2.88 (m, 4H, 2 CH2), 2.10 (s, 1H, NH)
2	11.28 (s, 1H, NH), 7.80 (d, J = 8.0 Hz, 1H, Ar), 7.00 (d, J = 8.0 Hz, 1H, Ar), 6.87–7.82 (m, 2H, Ar), 6.69–6.62 (m, 2H, Ar), 6.52–6.40 (m, 4H, Ar), 6.25 (d, J = 8.0 Hz, 1H, Ar), 4.73 (s, 1H, OH), 3.77–3.60 (m, 7H, 3 CH2 and CH), 3.24–3.08 (m, 6H, 3 CH2), 3.30 (s, 3H, OMe), 2.91 (m, 4H, 2 CH2), 2.11 (s, 1H, NH), 1.35 (m, 4H, 2 CH2), 0.98 (t, J = 7.5 Hz, 6H, 2 Me)
3	11.36 (s, 2H, 2 NH), 8.26 (d, J = 8.0 Hz, 2H, Ar), 7.49 (d, J = 8.0 Hz, 2H, Ar), 7.38–7.31 (m, 4H, Ar), 7.15–7.06 (m, 4H, Ar), 7.01–6.93 (m, 8H, Ar), 6.73 (d, J = 8.0 Hz, 2H, Ar), 4.35–4.23 (m, 6H, 2 CH2 and 2 CH), 3.75 (s, 6H, 2 OMe), 3.28–3.10 (m, 4H, 2 CH2), 2.10 (s, 2H, 2 NH), 1.79 (m, 8H, 4 CH2), 1.70 (m, 4H, 2 CH2), 1.57–1.53 (m, 4H, 2 CH2), 1.33 (t, J = 7.6 Hz, 4H, 2 CH2), 0.87 (t, J = 7.6 Hz, 6H, 2 Me)
4	11.37 (s, 2H, 2 NH), 8.27 (d, J = 8.1 Hz, 2H, Ar), 7.50 (d, J = 8.1 Hz, 2H, Ar), 7.39–7.31 (m, 6H, Ar), 7.16–7.12 (m, 4H, Ar), 7.03–6.89 (m, 6H, Ar), 6.74 (d, J = 8.1 Hz, 2H, Ar), 4.41–4.15 (m, 6H, 2 CH2 and 2 CH), 3.83–3.74 (m, 6H, 3 CH2), 3.59 (s, 6H, 2 OMe), 3.32–3.19 (m, 6H, 3 CH2), 2.32 (s, 2H, 2 NH), 0.84 (s, 6H, 2 Me)