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. 2021 Feb 5;22(4):1605. doi: 10.3390/ijms22041605
ND Neurodegenerative diseases
FNDC5 Fibronectin type III domain-containing protein 5
PeP Peroxisomal protein
FRCP2 Fibronectin type III repeat-containing protein 2
PGC-1 α PPARγ co-activator-1α
CSF Cerebrospinal fluid
UCP1 Uncoupling protein 1
MAPK Mitogen-activated protein kinases
AMPK 5′ adenosine monophosphate-activated protein kinase
PI3K Phosphatidylinositol 3-kinase
AKT Protein kinase B
STAT3 Signal transducer and activator of transcription 3
cAMP Cyclic adenosine 3′,5′-monophosphate
PKA Protein kinase A
CREB cAMP response element-binding protein
Mtss1L Metastasis-suppressor 1-like
CNS Central nervous system
PRRS Pattern-recognition receptors
PAMPs Pathogen-associated molecular patterns
DAMPs Damage–associated molecular patterns
IL Interleukin
TNF Tumor necrosis factor
ROS Reactive-oxygen species
NO Nitric oxide
TLRs Toll-like receptors
IFN-γ Interferon-γ
AD Alzheimer’s disease
PD Parkinson’s disease
BDNF Brain-derived neurotrophic factor
TrkB Tropomyosin receptor kinase B
ERK Extracellular-signal-regulated kinase
NF-κB Nuclear factor-kappa light chain enhancer of activated B cells
GSK-3 Glycogen synthase kinase 3
MKP-1 Mitogen-activated protein kinase phosphatase 1
JNK c-Jun N-terminal kinase
NLRP3 Nod-like receptor pyrin-3
COX-2 Cyclooxygenase-2
Opa1 Optic atrophy 1
ALS Amyotrophic lateral sclerosis
pTau Hyperphosphorylated tau
Amyloid-beta
APP Amyloid precursor protein
BACE1 Beta-site amyloid precursor protein cleaving enzyme 1
MPTP 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
BMSCs Bone marrow stromal cells