Figure 8.

Pathology Scores for Re-epithelialization. Sections were assessed by a Board-Certified Veterinarian Pathologist. (A,B) The number of slides receiving the designated score are indicated in (#) with the calculated percentages out of the 12 wounds for each treatment at each time point. Path Scores: 3 = Normal epidermis across entire wound bed; 2 = regenerating or hyperplastic with 100% coverage; 1 = partial epidermis; 0 = no epidermis. (C,D) Day 14 example of hematoxylin and eosin stained sections with a path score of “1” with the upper left image showing the entire biopsy punch. The area outlined with a green box is magnified and shown in the image to the lower right with scale bar = 250 µm. * = newly formed epidermis; @ = residual pieces of treatment in wound bed. Fetal bovine dermis (FBD); Fish skin graft (FSG).