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. 2021 Feb 5;13(2):120. doi: 10.3390/toxins13020120

Table 1.

BoNT-A treatment in bromhidrosis.

First Author [Ref.], year Type of Study n (site) BoNT-A Doses Retreatment Follow-Up Results
Wu [54], 2019 Prospective 19 (axilla) NA NA 3 months mean degree of malodor and mean sweat production in the BoNT-A-treated axilla were significantly lower than those in the control axilla at 3 months after therapy.
Wang [55], 2018 Prospective 62 adolescents (axilla) 50 U BoNT-a/axilla Yes The average follow-up was 2.64 years 82% of patients (51/62) ranked the BoNT-A treatment to be very good or good.
He [53], 2017 Prospective 53 (secondary bromhidrosis, axillae) 50 U BoNT-a/axilla NA 12months 48 patients ranked the satisfaction with BoNT-A treatment as “very good” or “good”
Lee [56], 2004 Cae report 1 (genitalia) 40 different sites (2.5 mU/0.1 mL per site) NA 9 months odorless and anhydrous response in the genital region,