Table 1.
BoNT-A treatment in bromhidrosis.
| First Author [Ref.], year | Type of Study | n (site) | BoNT-A Doses | Retreatment | Follow-Up | Results |
|---|---|---|---|---|---|---|
| Wu [54], 2019 | Prospective | 19 (axilla) | NA | NA | 3 months | mean degree of malodor and mean sweat production in the BoNT-A-treated axilla were significantly lower than those in the control axilla at 3 months after therapy. |
| Wang [55], 2018 | Prospective | 62 adolescents (axilla) | 50 U BoNT-a/axilla | Yes | The average follow-up was 2.64 years | 82% of patients (51/62) ranked the BoNT-A treatment to be very good or good. |
| He [53], 2017 | Prospective | 53 (secondary bromhidrosis, axillae) | 50 U BoNT-a/axilla | NA | 12months | 48 patients ranked the satisfaction with BoNT-A treatment as “very good” or “good” |
| Lee [56], 2004 | Cae report | 1 (genitalia) | 40 different sites (2.5 mU/0.1 mL per site) | NA | 9 months | odorless and anhydrous response in the genital region, |