Table 9.
Studies reporting the BoNT-A treatment in hidradenitis suppurativa.
| First Author [Ref.], year | Type of Study | n | BoNT-A Doses | Follow-Up | Retreatment | Results |
|---|---|---|---|---|---|---|
| O’Reilly [150], 2005 | Case report | 1 | 250 U Dysport/axilla | 10 months | No | Complete remission |
| Feito-Rodriguez [151], 2009 | Case report | 1 | 40 U total dose (inguinal folds) | 6 months | Yes | Complete remission |
| Khoo [152], 2014 | Case report | 3, but only 1 described | 50 U/axilla | 3 years | Yes (3 other times) | Complete remission |
| Shi [153], 2019 | Case report | 1 | 100 units for each area (bilateral axillary, inframammary and groin) |
NA | Yes (5 total injections) | Resolution of inflammation and healing of draining sinuses |
| Campanati [154], 2019 | Case report | 2 | 50 U per axilla 100 U for each side of groin |
1 year | Yes (for patient 1, after 10 months after the first injection) | Real improvement |
| Grimstad [156], 2020 | Randomised, Double-Blind, Placebo-Controlled Pilot Study | 20 | 150 U/armpit, 200 U/groin, and 600 U in the perianal/perigenital areas | 6 months | Yes (3 months after the first injection) | Clear improvement of the quality of life |