Table 10.
Androgenetic alopecia and BoNT injection therapy. FNS, finasteride.
| First Author [Ref.], year | Type of Study | n | BoNT Doses |
Follow-Up | Retreatment | Results |
|---|---|---|---|---|---|---|
| Freund [168], 2010 | Open-label pilot study | 50 male | 150 U | 60 weeks | Two treatment cycles of 24 weeks each | Treatment response rate was 75 percent |
| Singh [169], 2017 | Open-label pilot study | 10 male | 150 U | 6 months | No | Of 10 patients, 8 had good to excellent response on photographic assessment |
| Zhang [170], 2019 | Open-label pilot study | 24 male | 50 U | 6 months | No | Variable results |
| Shon [172], 2020 | Open-label pilot study | 18 male | 30 U | 6 months | Yes (every 4 weeks for 24 weeks). | Air density was significantly improved after 6 months but not after 3 months. |
| Zhou [173], 2020 | Opena label, randomized study (BoNT-A vs. BoNT-A+Finasteride) | 63 male and 1 woman | 100 U | 1 year | Yes (every 3 months) | BTA combined with FNS presents excellent results |