Table 3.
GR gene haplotypes frequencies and association with lifetime PTSD in war veterans.
| Haplotypes a | Haplotypes no. | No PTSD | PTSD | OR | CI (95%) | p-Value |
|---|---|---|---|---|---|---|
| CGACA b | Haplotype 1 | 0.445 | 0.385 | 1.00 | ||
| CGAGA | Haplotype 2 | 0.212 | 0.240 | 2.49 | 0.76–8.22 | 0.133 |
| TGAGA | Haplotype 3 | 0.143 | 0.107 | 1.57 | 0.38–6.52 | 0.532 |
| TGACG | Haplotype 4 | 0.127 | 0.203 | 19.03 | 1.59–227.92 | 0.020 |
| TAACG | Haplotype 5 | 0.039 | 0.031 | 0.84 | 0.08–8.33 | 0.881 |
| CGGCA | Haplotype 6 | 0.027 | 0.016 | 1.35 | 0.03–63.65 | 0.877 |
PTSD = Posttraumatic stress disorder. a Alleles are ordered according to the following SNPs (chromosome 5 DNA reverse strand): Tth111I (rs10052957) C/T, ER22/23EK (rs6189/rs6190) G/A, N363S (rs56149945) A/G, BclI (rs41423247) C/G, and 9β (rs6198) A/G; b The most frequent haplotype (CGACA) was used as a reference; associations with p-value < 0.05 are highlighted in bold.