Table 1.
Sequence, genomic localization and nucleotide (nt) position of mutated Serine and Arginine Rich Splicing Factor 1 (SRSF1) binding sites (BSs) within Mut1, Mut2 and Mut3 circSMARCA5. Prediction of SRSF1 BSs was performed by RBPMap (http://rbpmap.technion.ac.il/).
| # | Mutated circSMARCA5 ID | Mutated Sequence of Predicted SRSF1 BS |
Predicted SRSF1 BS Genomic Localization (GRCh38/hg38 Assembly) |
Localization within circSMARCA5 (nt) |
|---|---|---|---|---|
| 1 | Mut 1 | TCTACTT | chr4:143543546–143543552 | 38–44 |
| 2 | ACTACTTCTA | chr4:143543615–143543624 | 107–116 | |
| 3 | Mut 2 | CGATCCA | chr4:143543627–143543633 | 119–125 |
| 4 | TCCACGT | chr4:143543645–143543651 | 137–143 | |
| 5 | Mut 3 | TCTACTTACT | chr4:143543860–143543869 | 157–166 |
| 6 | GCTTCCTCTTCTG | chr4:143543942–143543954 | 239–251 |