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. 2021 Feb 7;12(2):237. doi: 10.3390/genes12020237

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The common differentially expressed genes and pathways between schizophrenia (SCZ) and type 2 diabetes mellitus (T2DM). (A) Venn diagram representing common differentially expressed genes (DEGs) between SCZ and T2DM, where up denotes upregulated and down denotes downregulated DEGs. (B) A functional network was constructed using the 28 common DEGs between SCZ and T2DM, using the GeneMania prediction server. Overall, the network included 47 nodes. Nodes colored in red represent the commonly upregulated DEGs, while nodes in blue represent the commonly downregulated DEGs between SCZ and T2DM. Nodes labeled in green represent the hub genes of the network.