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. 2021 Feb 9;18(4):1639. doi: 10.3390/ijerph18041639
bid bis in die: twice a day
BLRM Bayesian Logistic Regression Model
CRM Continual reassessment method
DLT dose-limiting toxicity
ICH International Conference on Harmonisation of Technical Requirements for
Registration of Pharmaceuticals for Human Use
MTD maximum tolerated dose
PMDA Pharmaceuticals and Medical Devices Agency