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. 2021 Feb 9;22(4):1741. doi: 10.3390/ijms22041741

Figure 1.

Figure 1

Regulation of inflammatory response. Dotted lines indicate presumable mechanisms, normal lines indicate known activation. PAMPs: molecular patterns associated with pathogens, DAMPs: molecular patterns associated with danger, LPS: Lipopolysaccharide, TRIF: TIR-domain-containing adapter-inducing interferon-β, TRAF: TNF receptor-associated factor, Myd88: Myeloid differentiation primary response 88, NF-kB: nuclear factor kappa-light-chain-enhancer of activated B cells, IKK: IκB kinase, MAPK: mitogen-activated protein kinase, AP: Activator protein, IRF: Interferon regulatory factors.