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Binding sites of transcription factors (from proximal to distal) of human MVP promoter and their transcriptional effects (when known).
| Binding Site | Transcription Factor | Transcriptional Effect | Reference |
|---|---|---|---|
| STAT1 | STAT1 | Activation | [132] |
| p53 | - | - | [127] |
| GC | Sp1 | Activation | [128] |
| E-box | USF1 | Activation | [113] |
| GATA-box | - | - | [126] |
| MyoD | - | - | [126] |
| CCAT-box (Y-box) | p53; Y-box-binding protein | Repression | [133] |
| Upstream CBF1-binding site | N1ICD Notch1 fragment; CBF1 | Activation | [129] |
