Photomicrographs at the panoramic reconstruction of histological sections (×6.3) for the experimental groups (CG (clot group), BG(Bio-Gide® group), and PCL(polycaprolactone group)) in all periods analyzed (7, 15, 30, and 60 days postoperatively). The BG and PCL groups performed better at 60 days, demonstrating the ability to close the bone defect. The PCL group showed good closure of the defect, with particles of polycaprolactone and nanohydroxyapatite (nHA) surrounded by osteoid tissue. Asterisks (*) represent regions of bone stumps; plus signs (+) represent the horizontal extension of the bone defect.