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. 2021 Feb 9;13(4):711. doi: 10.3390/cancers13040711

Figure 4.

Figure 4

A dual role of NK cells in oncolytic virus therapies. Due to their ability to recognize and kill virus-infected cells, NK cells can cause a premature elimination of the virus, limiting its efficacy (A). However, thanks to this ability, NK cells can also enhance the clinical response by eliminating tumor cells in later stages of oncolytic virus (OV) therapy (B).