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. 2021 Feb 9;26(4):919. doi: 10.3390/molecules26040919

Scheme 3.

Scheme 3

Passerini and Ugi reactions using phenylglyoxal and 3-bromopropionic acid and X-ray molecular structure of lactame 9. The ORTEP plot is at the 30% probability level. Hydrogen atoms, except that of the NH fragment, have been omitted for the sake of simplicity.