Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 9;10(2):360. doi: 10.3390/cells10020360

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Long-term effects on spatial and cued fear memory dynamics induced by SDS, SPS, or the combination of both stressors. Long-term effects induced by SDS, SPS, or both stressors in the Morris water maze on (a) escape latencies across trials during each day of the acquisition phase, (b) the latency to cross the platform location, and (c) the number of crossings over the platform location during the probe session. Long-term effects induced by SDS, SPS, or both stressors in the auditory fear conditioning paradigm on (d) percentage of time spent in freezing during the first and last tone presentations at conditioning (day 1), (e) mean percentage of time spent in freezing during the three blocks of four trials each at extinction (day 2), (f) mean percentage of time in spent freezing during all eight trials at extinction retrieval (day 3). *, p < 0.05 vs. CTRL-CTRL group; §, p < 0.05 vs. CTRL-CTRL group; #, p < 0.05 vs. CTRL-SPS group; ##, p < 0.01 vs. CTRL-SPS group. (N = 8–11 rats per group or N = 8–12 rats per group, in the Morris water maze or auditory fear conditioning tasks, respectively).