Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A: CpG islands of actively transcribed genes are unmethylated and have trimethylation at histone H3lysine residue K4 (H3K4Me3) and acetylation on lysine residues at histones H3 and H4. B:Methylation of the CpG island is frequently associated with trimethylation of lysine residue K27 or trimethylation of lysine residue K9 at histone H3, coupled with loss of the active marks H3K4Me3 and acetylated H3 and H4.
