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. 2021 Feb 9;13(4):715. doi: 10.3390/cancers13040715

Figure 4.

Figure 4

AR expression and AR transcriptional activity in androgen and anti-androgen treated LNCaP cells. Relative fold AR expression measured in (A) transcript level by qRT-PCR assay and (B) protein level by SWATH-MS analysis. (C) Standardized gene expression (z-score) of the MSigDB Hallmark “Androgen Response” gene set in response to DHT, DHT + BIC, DHT + ENZ and EtOH/control treatments. (D) Relative fold protein expression of four ARGs; KLK3, FKBP5, NDRG1, UAP1 in response to DHT, DHT + BIC, DHT + ENZ, BIC, ENZ and control treatments. All measurements are normalized to control treatment. Error bars represent the means ± SD, * p < 0.05.