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. 2021 Feb 10;10(2):270. doi: 10.3390/antiox10020270
NAFLD Non-alcoholic fatty liver disease
MS Metabolic syndrome
IR Insulin resistance
CV Cardiovascular
HDL High density lipoproteins
FFAs Free fatty acids
ER Endoplasmic reticulum
PDFF Proton density fat fraction
MRI Magnetic resonance imaging
NASH Non-alcoholic steatohepatitis
HCC Hepatocellular carcinoma
T2DM Type 2 diabetes mellitus
BMI Body Mass Index
OGTT Oral glucose tolerance test
HbA1c Glycated hemoglobin
MAFLD Metabolic associated fatty liver disease
IRS Insulin receptor
PI3K Phosphatidylinositol 3-kinase
GLUT-4 Glucose transporter protein type-4
TNF-α Tumor necrosis factor-alpha
SREBP-1/2 Sterol regulatory element-binding protein-1/2
ChREBP Carbohydrate-responsive element-binding protein
PPAR-γ Peroxisome proliferator-activated receptor gamma
BA Bile acids
LPS lipopolysaccharides
SCFA Short-chain fatty acids
ROS Reactive oxygen species
O2•− superoxidation radicals
H2O2 Hydrogen peroxide
NADPH Nicotinamide adenine dinucleotide phosphate hydrogen
NF-κB Nuclear factor kappa B
JNK Jun N-terminal kinase
IKK Inhibitor of nuclear factor kappa-B kinase
EASL European Association for the Study of Liver
AASLD American Association for the Study of Liver Disease
PUFA Polyunsaturated fatty acid
MD Mediterranean diet
MUFA Mono-unsaturated fatty acid
IL Interleukin
LDL Low density lipoprotein
VLDL Very low density lipoprotein
SNPs Single nucleotide polymorphisms
PNPLA3 Patatin like phospholipase domain-containing protein 3
HSC Hepatic stellate cells
LXR Liver X receptor
MBOAT-7 Membrane Bound O-Acyltransferase Domain Containing 7
GCKR glucokinase regulatory protein
TGF-1 Transforming growth factor beta 1
PDGF Platelet-derived growth factor
HAT Histone acetyltransferase
HDAC Histone deacetylases
SIRT Sirtuins
SFAs Saturated fatty acids
EDHF hyperpolarizing factor of endothelial derivation
ED endothelial dysfunction
NOS Nitric oxide synthetase
ESM-1 Endocan
HMGB1 High mobility group box 1 protein
CAD coronary artery disease
HCV hepatitis C virus
HBV hepatitis B virus
US ultrasound
CAP Control attenuation parameter
IMT Intima-media thickness
CKD Chronic kidney disease
PIP3 Phosphatidylinositol (3,4,5)-trisphosphate
aPKC activated protein kinase C
AKT1 Protein kinase B
GSK3 Glycogen synthase kinase 3
mTOR Mammalian target of rapamycin
FOXO1 Forkhead box protein O1
PDK1 3-Phosphoinositide-dependent protein kinase 1
P phosphorylated