Table 1.
Fold change values of gene expression in patients with primary Sjögren Syndrome (pSS) plus extraglandular manifestations (EGMs)- pSS-EGMs, in patients with disease limited to glandular involvement (GI) plus widespread pain (WP)-pSS-WP, and in healthy controls (HCs).
| Gene | MX1 | IFIT1 | IFT3 | IFI44 | IDO1 | GBP1 | MIG | IP-10 | P2RY14 |
|---|---|---|---|---|---|---|---|---|---|
| pSS-EGMs | 85.9 | 38.5 | 24.4 | 40.4 | 25.1 | 8.3 | 4.5 | 1.5 | 5.5 |
| pSS-WP | 4.2 | 1.7 | 2.0 | 4.8 | 4.1 | 1.2 | 0.6 | 0.3 | 1.3 |
| HC | 2.1 | 1.6 | 1.1 | 1.5 | 1.4 | 1.3 | 1.5 | 1.3 | 1.4 |
Legend. IFN type I-induced genes: MX1, IFN-induced GTP binding protein 1; IFIT1, IFN-induced protein with tetratricopeptide repeats 1; IFIT3, IFN-induced protein with tetratricopeptide repeats 3; IFI44, IFN-induced protein 44. IFN type II-induced genes: IDO1, indolamine 2,3-deoxygenase 1; GBP1, guanylate binding protein 1; MIG, C-X-C chemokine 9 (CXCL9); IP-10, C-X-C chemokine 10 (CXCL10); P2RY14, purinergic receptor 14.